IndraLab

Statements

COPS6 inhibits CC. 4 / 4
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"Interestingly, our results indicated that autophagy is essential for decreasing CTSL, while CSN6 could inhibit the autophagy ability of CC cells."
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"We found that knockdown of CSN6 induced increased fluorescent protein mRFP+-GFP+-LC3 puncta, suggesting that CSN6 knockdown elicits autophagy flux in CC cells (Fig. 5D)."
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"To assess the metastatic effects of CSN6 in CC, we performed transwell assay and found that down-regulation of CSN6 strongly decreased the migration and invasion abilities of CC cells (Fig. 2H)."
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"Knockdown of CSN6 enhances autophagy in CC cells."
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