IndraLab

Statements


COPS5 decreases the amount of SMAD7. 1 / 3
1 |

"Here we report that Jab1/CSN5, which is a component of the COP9 signalosome complex, associates constitutively with Smad7 and that overexpression of Jab1/CSN5 causes the translocation of Smad7 from the nucleus to the cytoplasm, promoting its degradation"