IndraLab

Statements


USP6 activates response signature. 2 / 2
| 2

eidos
"This study demonstrates that high USP6 expression is associated with all of these hot TME hallmarks in ES patients , and that USP6 is sufficient to drive an IFN response signature and CXCL10 expression in vitro , as well as intra-tumoral immune cell recruitment and activation in vivo ."

eidos
"We found that USP6 is sufficient to trigger an IFN response gene signature , both in ES cells and other neoplastic models ( 17 ) ."