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USP1 deubiquitinates SIX1. 1 / 1

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"In addition, a recent report has shown that USP1 regulates the expression of cyclinD1 by deubiquitinating SIX1, and pharmacological or genetic inhibition of USP1 by ML-323 or siRNA downregulates the expression of SIX1 and cyclinD1, whereas the upregulation of USP1 increased the protein levels of SIX1 and cyclin D1 [41]."

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USP1 deubiquitinates SIX1. 1 / 1

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