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USP33 activates Glioblastoma. 2 / 2

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"Under hypoxic conditions, deubiquitinase USP33 promotes glioblastoma growth and maintains stemness of glioma stem cells by stabilizing hypoxia inducible factor-2α [12]."

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"USP33, for example, promotes pancreatic cancer malignancy through the TGFBR2/TGF-β pathway , while inhibiting USP2 expression conversely activates TGF-β signaling and fuels glioblastoma development ."

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USP33 activates Glioblastoma. 2 / 2

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