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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP7 activates TWIST1. 1 / 1

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"To substantiate the in vivo stabilization of HIF-1alpha by HAUSP, a transient co-transfection experiment showed that overexpression of HAUSP increased HIF-1alpha at the protein levels but not the mRNA levels (XREF_FIG and XREF_SUPPLEMENTARY), and further activated a Twist1 promoter driven reporter construct (XREF_FIG) XREF_BIBR."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...