IndraLab

Statements



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"C-Fos induction was blocked by TTX but not by AMPA or NMDA receptor antagonists, suggesting that c-Fos upregulation requires action potential firing, but not excitatory synaptic input."

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"Moreover, induction of both Arc and c-fos by DOI is attenuated by antagonists of 5-HT 2A and AMPA receptors (present data; Scruggs et al., 2000 )."

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"This finding strongly supports those of Scruggs et al. (2000) , who showed that AMPA/kainate receptor antagonism could completely block the c-Fos induction elicited by DOI in the cortex."