IndraLab
Statements
USP37 inhibits cell cycle. 2 / 2
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2
reach
"Established PLK1-dependent degradation substrates include EMI1 (Hansen et al. 2004; Moshe et al. 2004) and USP37 (Burrows et al. 2012), both of which antagonize the cell cycle E3 APC/C; WEE1 (Watanabe et al. 2004), which controls cyclin dependent kinase activity; and Claspin (Peschiaroli et al. 2006; Mailand et al. 2006; Mamely et al. 2006), which promotes DNA damage checkpoint signaling in S-phase."