IndraLab

Statements

KCNH2 inhibits terbinafine. 3 / 3
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"Deletion of either ROX1 transcriptional repressor or CTH1 and CTH2 post-transcriptional repressors of ERG1 expression led to an increase in Erg1 protein levels and terbinafine resistance."
35837730
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"In S. cerevisiae, Erg1 activity had been successfully decreased in several studies utilizing the inhibitor terbinafine, which resulted in clearly enhanced levels of squalene, while this study represents the first analysis of the effects of terbinafine on Erg1p in P. pastoris."
30197866
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"On the contrary, overexpression of CTH2 led to the opposite effect, lowering Erg1 levels and increasing terbinafine susceptibility."
35837730