IndraLab

Statements

USP15 activates pathway. 4 / 4
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"BRCA1 is a crucial component of the BRCC3 complex, leading to our conjecture that USP15 may activate the NF-κB pathway by deubiquitinating BRCC3, thereby augmenting its expression and ultimately influencing bladder cancer progression."
38656882
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"USP15 activates the TGF-β pathway, while its inhibition reduces TGF-β activity, suppressing Glioblastoma cell proliferation."
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"These results demonstrate that USP15 can activate the NF-κB pathway by modulating the levels of BRCC3."
38656882
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"PLOD2 has been shown to play an oncogenic role in colorectal carcinoma by upregulating USP15, which subsequently activates the AKT/mTOR pathway [ xref ]."
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