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USP25 inhibits MAPK. 2 / 2

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"USP25 inhibits the overactivation of the NF-κB and MAPK pathways by removing the K63 polyubiquitin chain on TAB2, thereby attenuating microglia-mediated neuroinflammation (103)."

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"The deubiquitinases (DUBs) A20 and USP25 negatively regulate IL-17-induced NF-kappaB and MAPK activation by removing ubiquitin modifications on TRAF6."

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IndraLab

Statements

USP25 inhibits MAPK. 2 / 2

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