IndraLab

Statements

C/VIF2 inhibits USP7. 4 / 4
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"Comparative kinetic analysis showed that while the vif1 peptide weakly attenuated HAUSP DUB activity, the vif2 peptide completely suppressed HAUSP DUB activity (XREF_FIG, right panel)."
22056774
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"2.5.2 Vif1 and vif2 : Peptide inhibitors of HAUSP deubiquitinase (US20140073585A1)."
26077642
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"These results thus further corroborate the notion that vif1 interferes with HAUSP substrate binding, while vif2 inhibits HAUSP DUB activity."
22056774
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"HAUSP regulates the activities of MDM2 and p53 by deubiquitination, while vif1 and vif2 antagonize HAUSP and promote p53 dependent apoptosis XREF_BIBR."
23816559