IndraLab

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USP36 increases the amount of RBM28. 3 / 3
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"Consistently, wild-type(WT) USP36 significantly increased RBM28 protein levels in a dose-dependent manner, whereas catalytic inactive mutant C131A (USP36 ) showed no obvious impact on RBM28 protein levels (Fig. 2H, I)."
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"These findings suggest an interaction between USP36 and RBM28.Next, we proceeded to investigate whether the expression levels of RBM28 are modulated by USP36."
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"However, there were no observable changes in the mRNA levels of RBM28 following USP36 knockdown or overexpression, which suggested that USP36 upregulates RBM28 expression through post-translational regulation (Fig. S2B)."
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