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USP9X activates PMAIP1. 2 / 2
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"Interestingly, both Usp9X pharmacological inhibition and silencing in MPNST cells elicited a significant increase in ATF3, a typical marker of ER-stress (Fig. 5a,b) and in the pro-apoptotic BH3-only protein Noxa (Fig. 5a,b)."

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"Furthermore, Usp9x expression increased in Noxa knockdown cells, suggesting Noxa may regulate Mcl-1 expression by controlling the expression of Usp9x."