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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP17L2 activates homologous recombination. 2 / 2

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reach

"Despite the above evidence, an independent group identified DUB3 in an RNAi screen where knockdown led to decreased BRCA1 and RAD51 foci, meaning DUB3 may promote HR as well [107]."

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reach

"Only a small number of DUBs strongly affected both 53BP1 and RAD51 recruitment simultaneously, including USP29, an enzyme linked to H2A de-ubiquitylation and the recently reported HR modulator DUB3."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...