IndraLab

Statements

Isoprenaline leads to the phosphorylation of KCNQ1. 3 / 3
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reach
"In the absence of AC9, isoproterenol stimulation of KCNQ1 phosphorylation in vivo and I Ks channel function in adult cardiomyocytes are nearly eliminated."
31769471
reach
"We have previously shown that adenylyl cyclase Type 9 (AC9) is associated with a KCNQ1, Yotiao, and PKA complex and facilitates isoproterenol stimulated phosphorylation of KCNQ1 in an immortalized cell line."
31461851
sparser
"Deletion of AC9 resulted in the loss of isoproterenol-stimulated KCNQ1 phosphorylation in vivo, even though AC9 represents less than 3% of total cardiac AC activity."
31461851