IndraLab

Statements

Pterostilbene inhibits NLRP3. 5 / 5
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"Due to pterostilbene’s capacity to block NLRP3 activation and EMT through autophagy activation, the data indicate that pterostilbene might be a new preventative and therapeutic agent for CKD [84]."
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"Autophagy is likely to be stimulated during AKI and repressed during CKD, and strategies to target downstream signaling pathways, such as NLRP3 inflammasome inhibition by pterostilbene to modulate autophagy could serve as novel therapeutic strategies to prevent the maladaptive repair in damaged renal cells during injury."
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"Pterostilbene, the substantial antioxidant in blueberries, remarkably reduced NLRP3 inflammasome, NF-κB expression, cardiac oxidative stress and inflammation via activating AMPK/Nrf2/heme oxygenase (H[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Furthermore, pterostilbene was able to inhibit the inflammasome NLRP3 and caspase -1 (CASP1) pathway, being a promising agent for the treatment of AD."
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"Pterostilbene inhibits amyloid-beta-induced neuroinflammation in a microglia cell line by inactivating the NLRP3 and caspase -1 inflammasome pathway."
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