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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

TGFA binds EPGN, EGF, EGFR, and AREG. 2 / 2

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➶

sparser

"These receptors form homo-/hetero dimers in response to ligand binding and each shows different specificity and affinity to its ligands; EGFR specifically binds to EGF, TGF-α, amphiregulin and epigen, both EGFR and HER4 bind to betacellulin, HB-EGF and epiregulin and HER3 and/or HER4 bind to the neuregulin family, EGF and TGF-α [ xref ]."

30404198

➶

sparser

"Among these, only EGF, TGFα, amphiregulin, and epigen associate specifically with the EGFR homodimer ( xref )."

29459028

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...