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BRCC3 binds NLRP3 and K63. 1 / 1

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"DUB BRCA1/BRCA2-containing complex subunit 3 (BRCC3) can directly bind to NLRP3 and cleave K63-linked polyubiquitin that is added by ubiquitin ligase RNF125 and subsequently facilitate NLRP3 inflammasome activation [124]."

36551253

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IndraLab

Statements

BRCC3 binds NLRP3 and K63. 1 / 1

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