IndraLab

Statements


USP18 ubiquitinates CSF1R. 2 / 2
| 2

reach
"These data indicate that USP18 inhibits the interaction of CSF1R and NEDD4, which diminishes the NEDD4-mediated ubiquitination of CSF1R and results in the inhibition of CSF1R degradation."

reach
"Similarly, USP18 binds the colony-stimulating factor 1 receptor (CSF1R) and blocks the interaction of CSF1R with the ubiquitin E3 ligase NEDD4 and the ubiquitination and degradation of CSF1R [94] (Figure 2)."