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PR-619 decreases the amount of USP48. 2 / 2

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"However, little is known about effects and mechanism of PR-619 in AML.In this study, we demonstrated that PR-619 reduces USP48 protein levels by promoting its cleavage in various leukemia cells."

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"Western blot analysis revealed that PR-619 reduced USP48 protein levels and promoted PARP cleavage (Figure 1c)."

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IndraLab

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PR-619 decreases the amount of USP48. 2 / 2

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