IndraLab

Statements

Lithium(1+) inhibits STAT1. 5 / 5
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"Lithium also inhibited STAT1 activation induced by IFN-beta with or without anti-CD3 costimulation (XREF_FIG)."
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"We then evaluated if lithium dependent inhibition of pSTAT1 would affect the generation and expansion of Th1 cells by MOG 35-55 restimulation under Th1 polarizing conditions (XREF_FIG)."
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"This result demonstrates that although lithium inhibits STAT1 activation initiated by IFNAR engagement (XREF_FIG), the type I IFN receptor is dispensable for lithium 's therapeutic activity in EAE (XREF_FIG)."
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"However, lithium did inhibit STAT1 activation in B-cells and CD8 + T cells (XREF_SUPPLEMENTARY)."
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"Both continuous and acute lithium treatment significantly inhibited STAT1 activation in Th1 cells (XREF_FIG)."
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