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OTUD1 inhibits MCF10A cells expressing RAS metastasis breast cancer cells mice. 1 / 1
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"Moreover , OTUD1 suppresses TGF-beta signaling and EMT in MCF10A cells expressing RAS and metastasis of breast cancer cells in mice , respectively , presumably through deubiquitylating SMAD7 thus enabling SMURF2 binding and subsequent TGFR turnover43 ."