IndraLab

Statements

XSN inhibits KCNH2. 2 / 2
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"In this study, we revealed that XSN blocks hNaV1.5 sodium channel and hERG potassium channel, which has placed XSN as a class I and III antiarrhythmic medicine as the widely used antiarrhythmic drug amiodarone."
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"As we reported previously that XSN blocked human hERG channels in a dose dependent manner with an IC 50 of 0.34 mg/ml; the data were applied to computational simulation of human AP."
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