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TGFB increases the amount of USP15. 2 / 3

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"Monoubiquitination of R-SMADs prevents the R, SMAD, and SMAD4 complex binding with the DNA, while USP15 reverses the modification and promotes TGFbeta dependent transcription."

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"In addition, in the presence of cycloheximide that blocks translation, the levels of USP15 increased by TGF-beta treatments were blocked (XREF_FIG)."

27893708

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IndraLab

Statements

TGFB increases the amount of USP15. 2 / 3

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