IndraLab

Statements

SNAP25 inhibits USP5. 3 / 3
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"A kinetics assay showed that isopeptidase T activity plateaued after 60 minutes, and SNAP concentrations above 250 mumol/L significantly inhibited isopeptidase T activity (XREF_FIG)."
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"Increasing concentrations of SNAP led to significantly increased inhibition of isopeptidase T activity (P <.001 at SNAP> = 500 mumol/L) (XREF_FIG)."
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"DTT significantly prevented SNAP mediated inhibition of isopeptidase T activity, restoring activity to 77.8% of control (* P <.001 vs control; ** P <.001 vs SNAP) (XREF_FIG)."
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