IndraLab

Statements

USP4 increases the amount of ARHGDIA. 3 / 3
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"The reduction in USP4 expression decreases the level of ELAVL1 protein deubiquitination, leading to decreased ELAVL1 protein expression and increased ARHGDIA expression, promoting bladder cancer cell migration and invasion [98]."
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"And downregulated USP4 promotes ARHGDIA expression by reducing ELAVL1 protein, thus accelerating invasion and metastasis of PCa."
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"The decreased USP4 mRNA could enhance Rho GDP dissociation inhibitor α (ARHGDIA) expression via the METTL3-USP4-ELAVL1 axis, which finally promotes the progression of PCa cells."
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