IndraLab

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USP20 activates Atherosclerosis. 3 / 3

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"In conclusion, inhibition of Usp20 by an LNP–siRNA complex can alleviate hyperlipidemia and prevent atherosclerosis."

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"The results showed that silencing Usp20 by LNP-siRNA reduced lipid contents in serum, decreased body weight, and prevented atherosclerosis."

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"In Ldlr -/- mice, silencing Usp20 by siRNA decreased lipid levels and prevented atherosclerosis."

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INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

USP20 activates Atherosclerosis. 3 / 3

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