IndraLab

Statements

OTUD5 activates HYCC1. 6 / 6
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"Therefore, our results suggest that OTUD5 promotes HCC cell proliferation by increasing the stability of SLC38A1."
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"Taken together, these findings indicate that OTUD5 promotes HCC cell proliferation via SLC38A1."
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"Thus, the above evidence seems to support the high expression of OTUD5 in HCC, especially in HBV-related HCC.In our study, overexpression of OTUD5 promoted the proliferation of HCC cells, while OTUD5 knockdown inhibited cell proliferation, which was also confirmed in vivo."
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"Finally, OTUD5 knockdown markedly suppressed the growth of HCC cells in vivo."
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"OTUD5 promotes the proliferation of HCC cells."
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"CCK-8 assays verified that OTUD5 silencing decreased the viability of HCC cells (P < 0.05, Fig. 2B)."
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