IndraLab

Statements

OTUD1 binds IRF3. 10 / 10
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sparser
"Subsequent co-immunoprecipitation assay verified the association of OTUD1 with IRF3 ( Fig. 3 B)."
30100102
sparser
"In addition to T407P and G430V which are assumed to neutral mutations, other OTUD1 mutants impair its suppressive effects on innate immunity through blocking the association of OTUD1 with IRF3 or dire[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
30100102
biogrid
No evidence text available
30100102
biogrid
No evidence text available
30100102
biogrid
No evidence text available
30100102
sparser
"In addition to its role in T cell activation and function, FOXO3 elicits an inhibitory effect on the innate immune response through activation of OTUD1-IRF3 signaling."
30100102
biogrid
No evidence text available
30100102
sparser
"OTUD1 interacts with IRF3 to remove the K63-linked poly-ubiquitin chains on IRF3 and to suppress the interferon activity."
32151092
sparser
"We next used immunofluorescence assays to confirm the association of OTUD1 with IRF3."
30100102
biogrid
No evidence text available
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