IndraLab

Statements

USP9X deubiquitinates IQCB1. 3 / 3
1 | 2
reach
"Because USP9X deubiquitinates NPHP5 (XREF_FIG), we hypothesize that NPHP5 is prone to ubiquitination when its association with USP9X is compromised in G2/M."
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reach
"Only wild type USP9X could robustly deubiquitinate NPHP5 (XREF_FIG)."
28498859
ubibrowser
"NPHP5 directly binds to a deubiquitinating enzyme USP9X/FAM and two E3 ubiquitin ligases BBS11/TRIM32 and MARCH7/axotrophin. NPHP5 undergoes K63 ubiquitination in a cell cycle dependent manner and K48/K63 ubiquitination upon USP9X depletion or inhibition."
28498859