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ATXN3 activates BAX. 2 / 2

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"Therefore, one of the possible pathogenic mechanisms of SCA3 neurodegeneration is polyglutamine-expanded ataxin-3 activation of Bax-mediated mitochondrial apoptotic pathway."

21092747

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"Polyglutamine expanded forms of ataxin-3 and -7 induce the up-regulation of Bax in cerebellar neurons as a part of programmed cell death caused by poly (Q) cytotoxicity."

22511762

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IndraLab

Statements

ATXN3 activates BAX. 2 / 2

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