IndraLab

Statements

OTUD7B inhibits cell population proliferation. 9 / 9
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"Furthermore, the present study investigated whether OTUD7B inhibits the proliferation and stemness of breast cancer cells by regulating the protein stability of FOXM1."
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"These data indicated that OTUD7B knockdown may suppress the stemness and proliferation of MDA-MB-468 cells."
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"OTUD7B inhibits the proliferation and migration of breast cancer cells [17]."
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"OTUD7B knockdown effectively induced apoptosis and inhibited the proliferation in PC3 cells."
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"In addition, OTUD7B depletion significantly decreased ERalpha positive breast cancer cell proliferation and migration."
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"These results indicated that the functions of OTUD7B in cancer may be cancer dependent.In ERα-positive breast cancer, OTUD7B directly interacts with and stabilizes ERα and knocking down OTUD7B inhibits cell proliferation by promoting ERα degradation (15)."
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"Genetic and Pharmacological OTUD7B Inactivation Suppresses Leukemia Cell Proliferation."
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"We further found OTUD7B also governed various leukemia cell proliferation and 7Bi treatment efficiently reduced leukemia cell proliferation in vitro."
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"These results show that OTUD7B downregulation greatly inhibits cell proliferation and promotes apoptosis in PC3 cells."
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