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USP38 increases the amount of VEGFA. 2 / 2

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"We next confirmed that overexpression of USP38 together with HIF1α apparently enhanced the expression of BNIP3, LDHA, PDK1 and VEGFA (Fig. 1A)."

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"In the USP38-deficient H1299 cell, reconstitution of wild-type USP38 dramatically upregulated VEGFA expression, but reconstitution of the mutant, USP38-C454S/D918N, did not do so (Fig. 3, G and H)."

38072059

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IndraLab

Statements

USP38 increases the amount of VEGFA. 2 / 2

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