IndraLab

Statements


USP9X leads to the deubiquitination of PRKAA2. 2 / 2
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"As expected, overexpression of USP9X reduced ubiquitination of PRKAA2 (Figure 7A)."

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"In our study, we identified USP9X as a novel deubiquitinase of PRKAA2 based on the following evidence: (1) USP9X interacted with PRKAA2; (2) USP9X significantly reduced the ubiquitination of PRKAA2; and (3) a loss-of-function mutant of USP9X as well as USP9X inhibitor WP1130 abolished its deuibiquitinating activity on PRKAA2."