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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

CYLD activates Leu-Met. 2 / 2

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"In good agreement, we also observed that increased IL-6 production of Cyld -/- mice upon high-dose Lm infection correlated with an augmented recruitment of neutrophils causing an improved control of Lm in the liver."

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"In good agreement with an inhibitory role of CYLD on NF-kappaB activity in macrophages (XREF_FIG) and on STAT3 activation in hepatocytes (XREF_FIG), increased hepatic CYLD production of Lm infected WT mice correlated with a reduced and delayed phosphorylation of p65, JAK2 and STAT3 as compared to Cyld -/- mice (XREF_FIG)."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...