IndraLab

Statements

CYLD activates Leu-Met. 2 / 2
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"In good agreement with an inhibitory role of CYLD on NF-kappaB activity in macrophages (XREF_FIG) and on STAT3 activation in hepatocytes (XREF_FIG), increased hepatic CYLD production of Lm infected WT mice correlated with a reduced and delayed phosphorylation of p65, JAK2 and STAT3 as compared to Cyld -/- mice (XREF_FIG)."
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"In good agreement, we also observed that increased IL-6 production of Cyld -/- mice upon high-dose Lm infection correlated with an augmented recruitment of neutrophils causing an improved control of Lm in the liver."
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