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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

Beta 4 subunit activates KCNMA1. 1 / 1

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"While the beta 4 subunit has been shown to play a critical role in mediating tolerance to alcohol induced modulation of BK channel function, CaMKII phosphorylation of Thr107 of the alpha subunit of BK channels increased channel activity and mediated the switch from alcohol induced activation of the channel-to-channel inhibition."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...