IndraLab

Statements

REST increases the amount of USP37. 3 / 3
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"Regulation of USP37 Expression by REST associated G9a dependent Histone Methylation."
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"Notably, Das et al. reported that REST induces medulloblastoma oncogenesis by repressing USP37 transcription, thereby leading to low levels of the p27 tumor suppressor, which controls proliferation and cell cycle exit by inhibiting CDK1 in cerebellar progenitor cells."
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"Like p27, a reciprocal association between USP37 and REST is present, and REST KD increases USP37 mRNA levels."
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