IndraLab

Statements

PAN2 inhibits cell population proliferation. 4 / 4
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"This study demonstrates that USP52 inhibits cancer cell proliferation through downregulation of cyclin D1 as well as AKT/mTOR signaling pathway inhibition."
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"USP52 inhibits cell proliferation by stabilizing PTEN protein in non-small cell lung cancer."
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"However, the simultaneous elimination of Pan2 and Ccr4 strongly impairs yeast cell proliferation, suggesting that these proteins have overlapping deadenylase activities [25] ."
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"In a similar vein, Zhu et al. demonstrated that USP52 stabilizes PTEN, downregulates cyclin D1, and inhibits the AKT/mTOR pathway, thereby suppressing cancer cell proliferation (41)."
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