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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

KCNMA1 activates signal transduction. 2 / 2

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"The open probability of BK channel was enhanced after activating NPRA/cGMP/PKG signaling pathway, and the cell membrane was hyperpolarized through phosphorylation of BK channel [32–34]."

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"SLO, binding to TLR4, activates the TRIF- and MyD88 dependent signalling pathway, which by inducing p38 MAPK activation, provokes the phosphorylation of cPLA 2, which in turn provides the arachidonic acid to be oxidized by 5-LO, thereby activating the cascade leading to CysLTs production."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...