IndraLab

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"Also, the voltage dependence of the HERG channel blockade by the BuOH (XREF_FIG) and H 2 O fractions (XREF_FIG) indicate that this drug preferentially blocks HERG channels in the closed state rather than either the open or inactivated states."

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"These findings indicate that HERG channels are also greatly blocked by BuOH fraction of L. erythrocarpa while remaining at the holding potential."