IndraLab

Statements

KCNH7 activates ergosterol. 5 / 5
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"Expression of C. reinhardtii ERG3 cDNA in erg3 null yeast was able to restore ergosterol biosynthesis and reverse phenotypes associated with lack of ERG3 function."
20084111
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"These experiments demonstrate that expression of ERG3 from C. reinhardtii can restore ergosterol biosynthesis in erg3Delta yeast."
20084111
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"Therefore, it is possible that decreased ERG3 expression by tsa3 mutation may further decrease cellular ergosterol content and exacerbate cell viability in addition to the effect by Erg11 inhibition with fluconazole."
23998805
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"Reintroduction of a wild-type ERG3 allele into the homozygous deletion mutant restored virulence, ergosterol synthesis, and susceptibility to azoles, confirming that these phenotypic changes were solely due to the inactivation of Erg3p."
16127034
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"S. cerevisiae erg3 null mutants are viable, but are unable to synthesize ergosterol XREF_BIBR."
26876023