IndraLab

Statements

OTUB1 activates HIF. 6 / 6
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"Furthermore, we examined whether the upregulation of HIF activation by OTUB1 was dependent on VHL."
35732631
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"Considering that FIH modulates OTUB1 activity, we subsequently examined whether the upregulation of HIF activation by OTUB1 is dependent on FIH."
35732631
reach
"These data suggest that OTUB1 enhances HIF transactivity under hypoxia.Given that PHDs-mediated HIF-α hydroxylation represents a main regulatory manner of HIF function [1, 21–23], we next sought to determine whether the upregulation of HIF activation by OTUB1 was dependent on PHDs."
35732631
reach
"Furthermore, we examined whether the upregulation of HIF activation by OTUB1 was dependent on VHL."
35732631
reach
"Considering that FIH modulates OTUB1 activity, we subsequently examined whether the upregulation of HIF activation by OTUB1 is dependent on FIH."
35732631
sparser
"Given that PHDs-mediated HIF-α hydroxylation represents a main regulatory manner of HIF function [ xref , xref – xref ], we next sought to determine whether the upregulation of HIF activation by OTUB1 was dependent on PHDs."
35732631