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USP2 activates MYLIP. 2 / 2

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"Such a temporal expression pattern would leave little opportunity to alleviate the USP2 mediated antagonism of IDOL, and the tripartite complex model would imply that IDOL is constantly engaged in a futile reaction, in which its ubiquitylation of LDLR is immediately reversed by USP2."

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"As expected of an interacting DUB, USP2 decreased the ubiquitylation and increased the protein stability of IDOL."

26846634

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IndraLab

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USP2 activates MYLIP. 2 / 2

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