IndraLab

Statements

KCNK2 activates potassium(1+). 5 / 5
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"Fluoxetine, a commonly used antidepressant, was reported to block the currents of several potassium channels, which are mediated by Kv1.1, Kv1.3, Kv1.4, Kv1.5, Kv3.1, Kv4.3, hERG and TREK-1 XREF_BIBR, XREF_BIBR, XREF_BIBR, XREF_BIBR, XREF_BIBR, XREF_BIBR, XREF_BIBR, XREF_BIBR, XREF_BIBR."
26579425
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"l-Lactate-induced TREK1 upregulation is a novel finding of physiological significance as TREK1 channels contribute to neuroprotection by enhancing potassium buffering and glutamate clearance capacity of astrocytes."
27062641
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"TREK-1 may modulate potassium current of glomus cells and/or afferent nerve endings in the rat carotid body."
16344329
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"Based on previous and current studies, astrocytic TWIK-1 and TREK-1 increased by AEG-1 potentially contribute to the protection of excitatory neuronal death by absorbing extracellular potassium ions secreted from activated neurons under pathological conditions."
33440655
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"Initially the inhibition of the TREK 1 channel causes dissociation of the C-terminal domain from the cell membrane and prevents the passage of potassium ions."
28928667