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COPS5 deubiquitinates HSPA. 6 / 6
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"In addition, CSN5 can deubiquitinate Snail and heat shock protein 70 (HSP70), thereby enhancing tumor invasion and metastasis (Hu et al., 2021)."
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"For instance, deubiquitination of HSP70 by CSN5 were reported to modulate exosomal protein sorting and to enhance cancer cell progression [ 26 ]."
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"For instance, deubiquitination of HSP70 and Snail by CSN5 were reported to modulate exosomal protein sorting and to enhance cancer cell invasion and migration, respectively."
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"Deubiquitination of HSP70 by CSN5 were reported to modulate exosomal protein sorting in a deubiquitinating activity-dependent manner [27] ."
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"For instance, the deubiquitination of HSP70 and Snail induced by CSN5 regulated exosomal protein sorting and enhanced the invasion and migration of cancer cells [36,37]."
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"For instance, deubiquitination of HSP70 and Snail by CSN5 were reported to modulate exosomal protein sorting and to enhance cancer cell invasion and migration, respectively [ 24 , 25 ]."
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