IndraLab

Statements

MALT1 activates TNFAIP3. 2 / 2
| 2
reach
"In turn, MALT1 mediates rapid proteolytic cleavage and inactivation of TNFAIP3 after TCR stimulation, thus fine tuning TCR activation 21."
32709905
reach
"While MALT1 scaffolding activates NF-κB and transcriptional induction of the TNFAIP3/A20 gene, MALT1 protease also cleaves and inactivates the RNA binding protein (RBP) Roquin-1 and thereby enhances A20 expression on the post-transcriptional level (48, 49) (see chapter 3)."
38863711