IndraLab

Statements

DiUb binds OTUD7A. 2 / 2
| 2
reach
"Reactive diUb-Cez2 complex configurations were identified, which lead to isopeptide bond cleavage and stabilization of the tetrahedral oxyanion intermediate."
39782030
reach
"In combination with a high per-residue model confidence score (pLDDT score of 88.59 ± 14.18), the top-ranked model for the OTU domain was considered as a starting structure for Cezanne-2 and selected for subsequent refinement steps.As a model for the diUb-bound Cez2 enzyme–substrate complex, we used a combination of the AF2 prediction and structural alignment."
39782030