IndraLab

Statements

Integrins activates KCNMA1. 6 / 6
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"Likewise, BK channel potentiation by alpha5beta1 integrin activation requires c-Src phosphorylation of the channel alpha-subunit at residue Tyr 766."
20549941
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"XREF_BIBR have shown that alpha v beta 1 integrin activation potentiates BK channel activity in vascular smooth muscle."
19808102
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"Our results show that alpha5beta1 integrin activation potentiates BK channel activity in vascular smooth muscle through both Ca (2+) - and c-Src-dependent mechanisms."
18218680
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"Fibronectin, an alpha5beta1 integrin ligand, enhanced BK channel activity through Ca 2+ and phosphorylation dependent mechanisms in VSMC."
26049174
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"Thus, BK channel activity is enhanced by alpha5beta1 integrin activation, likely through an intracellular signaling pathway involving c-src phosphorylation of the channel alpha-subunit at Tyr 766."
19887442
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"Recently, we found that fibronectin, an endogenous alpha5beta1 integrin ligand, enhances BK channel current through both Ca (2+) - and phosphorylation dependent mechanisms in vascular smooth muscle."
19887442