IndraLab

Statements


USP8 leads to the phosphorylation of STAT3. 2 / 2
| 2

reach
"USP8 knockdown did not affect STAT3 phosphorylation in ARID1A-proficient RMG-I cells but attenuated STAT3 phosphorylation in ARID1A-deficient RMG-V and OVTOKO cells (Fig. 5C)."

reach
"Deficiency of ARID1A causes abnormalities in the STAT3 pathway, which is one of the downstream pathways of FGFR2, but suppression of USP8 attenuates phosphorylation of STAT3 pT705 and induces apoptosis."